Early findings from researchers at Children’s Hospital of Philadelphia (CHOP) show that convalescent plasma appears to be a safe and possibly effective treatment for children with life-threatening cases of COVID-19. The results were published online Friday by the journal Pediatric Blood and Cancer.
To date, no therapies have been proven safe and effective for children who develop life-threatening complications from contracting the SARS-COV-2 virus. One possible treatment that has been explored in adults is the use of convalescent plasma, which is derived from patients who have recovered from COVID-19 and can be administered in currently ill patients to generate an antibody response that renders the virus inert. Early positive results were observed in adults who received convalescent plasma, but the treatment had not been studied in children.
“Some children who contract this virus can develop very serious complications, so even with limited data in adults, we believed it was worth exploring the use of convalescent plasma as a possible treatment option,” said David Teachey, MD, senior author of the study and an attending physician, Co-Leader of the Immune Dysregulation Frontier Program, and Director of Clinical Research at the Center for Childhood Cancer Research at CHOP.Original Source